BURNHAM INSTITUTE FOR MEDICAL RESEARCH; INC.;DANA-FARBER CANCER INSTITUTE;DANA-FARBER CANCER INSTITUTE, INC.
发明人:
MARASCO, WAYNE, A,SUI, JIANHUA,LIDDINGTON, ROBERT, C
申请号:
NZ58661108
公开号:
NZ586611A
申请日:
2008.12.08
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed are human scFv antibodies and monoclonal antibodies that neutralize influenza virus. The antibodies recognize an epitope in the stem region of the hemagglutinin (HA) protein. Also provided are methods of treating and/or preventing a influenza related disease or disorder such bird flu The invention also provides methods of vaccinating a patient against influenza. Also provided are methods of diagnosing influenza- related diseases or disorders and methods of detecting the presence of a influenza in a sample.