Qiao Lin,Yibo Zhu,Junyi Shang,Zhixing Zhang,Xuejun Wang,Jaeyoung Yang,Cheng Wang
申请号:
US15374375
公开号:
US20170181669A1
申请日:
2016.12.09
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A receptor capable of binding to the target analyte can be used in monitoring a target analyte in a bodily fluid or a sample. A microdevice in accordance with the disclosed subject matter can include a substrate and a conductance elements with receptors grafted on the surface of the conductance element. A microdevice in accordance with the disclosed subject matter can also include a substrate, a first and second conductance elements, and synthetic polymers grafted on the surface of the first and second conductance elements. The first conductance element can be grafted with a sensing polymer that binds the target analyte, and the second conductance element can be grafted with a reference polymer that is insensitive to the target analyte. Differential measurement of the graphene conductance can allow determination of target analyte concentration in a bodily fluid.