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MESALAZINE TABLET HAVING IMPROVED DISSOLUTION
专利权人:
Disphar International B.V.
发明人:
De Fluiter, Hendrick Cornelis
申请号:
AU2016210591
公开号:
AU2016210591A1
申请日:
2016.08.01
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
#$%^&*AU2016210591A120160818.pdf#####ABSTRACT The invention provides a method for preparing a mesalazine enteric coated tablet comprising (i) granulating a composition comprising mesalazine, a pharmaceutically accepted salt, or ester thereof, into mesalazine granulates (ii) tabletting a core composition comprising the mesalazine granulates obtained in (i) to obtain a tablet core (iii) coating the tablet core obtained in (ii) with at least an intermediate layer and an enteric coating where the tablet core hardness is controlled to be comprised between 80 N and 105 N and the intermediate layer represents less than 2% by weight of the tablet.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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