The present invention relates to a cosmetic composition and / or dermatological and / or therapeutic comprising at least one compound chosen from the group consisting of a mineral water comprising between 40 mg / l and 600 mg / 1 of calcium, and / or of salts and / or of derivatives that - c, between 12,5 mg / 1 and 125 mg / 1, magnesium and / or of salts and / or of derivatives that - c, between 0,455 mg / 1 and 45,5 mg / 1, and / or of salts and / or of derivatives that - c, between 23,6 mg / 1 and 2360 mg / 1, and / or of salts and / or of derivatives that - ci, the xanthan gum, an extract from ascophyllum nodosum, containing at least 30% of sulphated polysaccharides having an average molecular weight of 10000 daltons, an extract of ginseng, aqueous-alcoholic type obtained by percolation continues from the root entirely shut off and dried of panax ginseng, this extract is way of the ginsenoside in a proportion by mass of greater than or equal to 8%, this compound is chosen for its use as an inhibitor of the enzymatic activity of the klk5, the other ingredients are constituted by compounds that are acceptable in the cosmetic and / or dermatological and / or therapeutic.