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Liquid Carrier for Oral Delivery of a Pharmacologically Active Agent
专利权人:
Anders Carlsson
发明人:
Anders Carlsson,Bengt Herslöf,Jan Holmbäck
申请号:
US14112387
公开号:
US20140044779A1
申请日:
2012.04.20
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A fluid carrier comprises first and second substantially immiscible liquids. The first liquid is an open-chain silicone oil of the formula [(CH3)3Si—O]—[(CH2)2Si—O]n—[Si(CH3)3]. The second liquid is a polar lipid material. The first and second liquids are capable of forming an unstable dispersion. The unstable dispersion can be stabilized by adding a powderous solid insoluble in the liquids. The powderous solid is selected from pharmacologically active agent, pharmaceutical excipient, and their mixtures. The stabilized dispersion is of a creamy or ointment-like or mouldable form, and can be filled into capsules or moulded into tablets so as to be fit for peroral administration.
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