An energy delivery system may include an expandable member having a plurality of electrodes, including pairs of adjacent electrodes, and a generator configured to supply an electric voltage to each of the plurality of electrodes. The energy delivery system also may include a controller coupled to the plurality of electrodes and the generator. The controller may be configured to measure an impedance of tissue disposed between the electrodes of each pair of adjacent electrodes, and determine, based on the measured impedances, whether cancerous tissue is disposed between any of the electrodes of each pair of adjacent electrodes. The controller also may be configured to apply a voltage between the electrodes of each pair of adjacent electrodes determined to have cancerous tissue disposed between them.
