Oregon Health & Science University;The United States of America as respresented by the Department of Veterans Affairs
发明人:
Owen J. McCarty,Norah Verbout,Halina Offner-Vandenbark,Erik I. Tucker
申请号:
US15113200
公开号:
US10137177B2
申请日:
2015.01.21
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods of treating neuroinflammation by administration of a selective protein C activator, such as recombinant human WE thrombin and optionally one or more of its cofactors are disclosed. Also disclosed are pharmaceutical compositions for use in the treatment of mammals that exhibit symptoms of neurological inflammation. The pharmaceutical compositions and pharmacological dose comprise a safe and effective amount of WE thrombin.