A spacer device (1) for the two-step treatment of prosthesis infections, made from biologically compatible and porous material designed to allow the possibility of adding pharmaceutical products, active and/or therapeutic ingredients, includes a first portion (2) designed to be fixed to a corresponding bone bed remaining from a previous implant, and a second portion (3) designed to be inserted in a corresponding articular area of the patient, the first portion (2) and the second portion (3) being attached by adjustable connecting means (4).