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biphenyl amides with modified ether groups as hsp90 inhibitors and hsp70 inducers
专利权人:
THE UNIVERSITY OF KANSAS
发明人:
BRIAN S.J. BLAGG,MERCY ANYIKA,RICK T. DOBROWSKY
申请号:
BR112016029672
公开号:
BR112016029672A2
申请日:
2015.06.24
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
biphenyl amides with modified ether groups as hsp90 inhibitors and hsp70 inducers? Compounds of the formulas are provided herein: (i) wherein: n, x 2, r 3, r 3 ', r 4, r 4', r 5, r 5 ', r 6 and r 6' are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds may be used for the treatment of diseases, including diabetic peripheral neuropathy or cancer.resumo ?bifenil amidas com grupos éter modificados como inibidores de hsp90 e indutores de hsp70? são aqui fornecidos compostos das fórmulas: (i) em que: n, x2, r3, r3', r4, r4', r5, r5', r6 e r6' são como aqui definidos. as composições farmacêuticas dos compostos também são fornecidas. em alguns aspectos, estes compostos podem ser utilizados para o tratamento de doenças, incluindo a neuropatia periférica diabética ou câncer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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