PURPOSE: A composition containing Opuntia ficus-indica root extract or a fraction thereof is provided to prevent and/or treat diabetes and/or diabetes complication without toxicity and side effects. CONSTITUTION: A composition for preventing or treating diabetes or diabetes complication contains: Opuntia ficus-indica root extract obtained using water, straight or branched alcohol of C1-C4； and a fraction thereof obtained by fractioning the extract using water, alkane of C5-C7, straight or branched alcohol of C1-C4, methylene chloride, or ethylene acetate. A composition for preventing or treating diabetes or diabetes related complications contains the Opuntia ficus-indica root alcohol extract, hexane fraction, methylene chloride fraction, ethyl acetate fraction, alcohol fraction, or water fraction as an active ingredient.노팔(Opuntia ficus-indica) 뿌리의 추출물 또는 상기 추출물의 분획물을 유효성분으로 함유하는 당뇨 및/또는 당뇨합병증의 예방 및/또는 치료용 조성물이 제공된다.
