A pair of nestable caps are disclosed, each of the caps being sized and shaped to provide a protective union about a separated medical connector. The pair comprises a male cap and a female cap, each of which is configured to be adjoined to a complimentary cap to form a nested pair. The nested pair is sealed until separated for use, thereby maintaining sterility of the internal surfaces of the nested pair. An absorbent pad may be impregnated with antiseptic agent and enclosed within the pair to further enhance resulting sterility of each cap as it is used about a medical connector. One of the caps can include a scrubbing chamber having a disposable liner, a pad, and an antiseptic agent. Further, a pliable tube containing a frangible capsule may be coupled to one of the caps to provide antiseptic solution internal to the caps.
