ONO Pharmaceutical Co., Ltd.;Kyoto Prefectural Public University Corporation
发明人:
申请号：
EP18866576.4
公开号：
EP3695839A1
申请日:
2018.10.12
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention addresses the problem of finding an effective method for treating solid cancers and providing a pharmaceutical product therefor. The present invention provides a therapeutic agent for solid cancers, which contains N-{5-[(6, 7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl}-2, 5- dioxo-1-phenyl-1, 2, 5, 6, 7, 8-hexahydro-3-quinolinecarboxamide, a pharmaceutically acceptable salt thereof, or a hydrate of the compound or the salt as an active ingredient, and which is characterized by being administered in combination with osimertinib or a pharmaceutically acceptable salt thereof. The combination of the present invention exerts a strong antitumor effect, and is therefore useful for treatment of solid cancers.
