Chemically Modified Factor IX

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专利权人:

BAXTER INTERNATIONAL INC.

发明人:

TURECEK, PETER,SCHEIFFLINGER, FRIEDRICH

申请号：

NZ59819308

公开号：

NZ598193A

申请日:

2008.12.19

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed is a blood coagulation factor IX (FIX) with a FIX activation peptide region (AP region), wherein said AP region comprises a covalently coupled water-soluble hydrophilic polymer absent from biologically produced FIX, said covalently coupled water-soluble hydrophilic polymer being hydroxyethyl starch (HES) attached to said FIX via Asn-157 and/or Asn-167 of said FIX.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/