INSTITUT GUSTAVE ROUSSY;ROBERTI Maria Paula;ZITVOGEL Laurence
发明人:
ZITVOGEL Laurence,ROBERTI Maria Paula
申请号：
IL27378220
公开号：
IL273782D0
申请日:
2020.04.02
申请国别(地区):
IL
年份:
2020
代理人:
摘要：
The invention relates to the prognosis and treatment of colon cancer. In particular, the present invention concerns the role of intestinal microbiota in the anticancer immune response elicited by ileal enterocytes succumbing to apoptosis, and provides immunogenic compositions for treating colorectal cancer (CRC), as well as signatures for prognosing CRC evolution. Specifically, it relates to composition comprising life bacteria of the family Erysipelotrichaceae except Solobacterium) and/or Rikanellaceae for use in the treatment of CRC, to a method of obtaining immunogenic enteroids and T follicular helper cells, also used for treating CRC.
