Chen, Xi,Dragoli, Dean R.,Fan, Pingchen,Li, Yandong,Powers, Jay P.,Punna, Sreenivas,Tanaka, Hiroko,Zhang, Penglie
申请号:
AU2013308988
公开号:
AU2013308988A1
申请日:
2013.08.27
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.