Merck Sharp & Dohme Corp.;MSD R & D (China) Co. Ltd.
发明人:
申请号:
EP15769367.2
公开号:
EP3122346A4
申请日:
2015.03.23
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention is directed to six membered heteroaryl benzamide compounds of formula (I), which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.