DERIVES DE 2-ADAMANTYLUREE EN TANT QU'INHIBITEURS SELECTIFS DE 11.BETA.-HSD1

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专利权人:

MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG

发明人:

CARNIATO, DENIS,CHARON, CHRISTINE,GLEITZ, JOHANNES,ROCHE, DIDIER,HOCK, BJOERN

申请号：

CA2633186

公开号：

CA2633186C

申请日:

2006.11.22

申请国别(地区):

CA

年份:

2014

代理人:

摘要：

The present invention relates to 2-adamantylurea derivatives of formula (I) asselective inhibitors of the enzyme11-beta-hydroxysteroid dehydrogenase type 1(110-HSD1) and the use of suchcompounds for the treatment and prevention ofmetabolic syndrome, diabetes, insulin resistance, obesity, lipid disorders,glaucoma, osteoporosis, cognitive disorders, anxiety,depression, immune disorders, hypertension and other diseases and conditions.

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中国工程科技知识中心

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