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Bile acid recycling inhibitors for treatment of hypercholemia and cholestatic liver disease
专利权人:
Lumena Pharmaceuticals LLC
发明人:
Gedulin, Bronislava,Grey, Michael,O'Donnell, Niall,ODonnell, Niall
申请号:
AU2012328453
公开号:
AU2012328453B2
申请日:
2012.10.26
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
Provided herein are methods of treating or ameliorating hypercholemia or a cholestatic liver disease by administering to an individual in need thereof a therapeutically effective amount of an Apical Sodium- dependent Bile Acid Transporter Inhibitor (ASBTI) or a pharmaceutically acceptable salt thereof. Also provided are methods for treating or ameliorating a liver disease, decreasing the levels of serum bile acids or hepatic bile acids, treating or ameliorating pruritis, reducing liver enzymes, or reducing bilirubin comprising administering to an individual in need thereof a therapeutically effective amount of ASBTI or a pharmaceutically acceptable salt thereof.
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中国工程科技知识中心
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