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METHODS FOR PRODUCING STABLE THERAPEUTIC GLUCAGON FORMULATIONS IN APROTIC POLAR SOLVENTS
专利权人:
XERIS PHARMACEUTICALS; INC.
发明人:
PRESTRELSKI, STEVEN,DONOVAN, MARTIN,SANDOVAL, MICHAEL
申请号:
CA2999404
公开号:
CA2999404A1
申请日:
2016.09.25
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Certain embodiments are directed to a formulation of a therapeutic agent, as well as a method of making such a formulation, comprising at least one therapeutic agent dissolved in an aprotic polar solvent system comprising at least one ionization stabilizing excipient in a concentration sufficient to impart physical and chemical stability to the therapeutic agent.
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