<;P>;PROBLEM TO BE SOLVED: To provide a drug and a method useful for preventing development and/or amelioration of symptoms of allergy diseases safely with no burden on patients. <;P>;SOLUTION: There are provided the antiallergic drug for oral administration, containing lactic acid bacteria and antigenic substances, a method of treating allergy diseases including orally administering a composition containing lactic acid bacteria and antigenic substances, and the use of lactic acid bacteria and antigenic substances in the production of antiallergic drugs. More specifically, as lactic acid bacteria, lactic acid bacteria having the effect of enhancing the development of inhibitory stimulus molecules PD-L2 on antigen presentation cells, for example, Lactobacillus paracasei KW3110 are used. <;P>;COPYRIGHT: (C)2011,JPO&INPIT