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Cell line stably expressing mutated oncoprotein E6 and method of screening anticancer compound of uterine cervical cancer using the same
专利权人:
Jee Eun Rhee
发明人:
Jee Eun Rhee,Dae Ho Jang,Sung Soon Kim,Byeong Sun Choi
申请号:
US12795211
公开号:
US08835164B2
申请日:
2010.06.07
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed are a cell line that expresses protein of Seq. No. 1, and a method for screening an anticancer compound of uterine cervical cancer by using the same. The stable cell line that expresses oncoprotein E6 of a human papillomavirus type 16 variant strain is used to determine a difference in amounts of expression of tumor suppressor genes, such as p53, between E6 protein of the reference strain and E6 protein of a variant strain, thereby screening an anticancer compound of uterine cervical cancer, etc. Further, it is possible to develop an anticancer agent of uterine cervical cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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