Olga LABOVITIADI,Wouter Frank TONNIS,Francesco DORO,Janik ADRIAANSEN
申请号:
US16709223
公开号:
US20200101167A1
申请日:
2019.12.10
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Compositions and methods for inducing an immune response against extra-intestinal pathogenic Escherichia coli (ExPEC) are described. In particular, multivalent vaccines containing O-antigen polysaccharide covalently bound to an exotoxin A of Pseudomonas aeruginosa (EPA) carrier protein that can withstand multiple environmental stresses are described.