The present invention generally relates to the field of preventing and/or treating inflammatory and infectious disorders, in particular by boosting the endogenous antimicrobial defences. One embodiment of the present invention is the use ofB. longumNCC2705 (deposit number CNCM I-2618) for use in the treatment or prevention of disorders related to the immune system including infections.本發明大體上係關於預防及/或治療發炎性及感染性病症之領域,特定言之其係藉由加強內源性抗菌性防禦。本發明之一項實施例為一種以長雙歧桿菌NCC2705(B. longum NCC2705)(寄存編號CNCM I-2618)於治療或預防與免疫系統相關之病症(包括感染)上之用途。