The invention relates to the compounds of formula I and formula II or its pharmaceutical acceptable salts as well as polymorphs solvates enantiomers stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I or formula II and methods for treating or preventing multiple sclerosis may be formulated for oral buccal rectal topical transdermal transmucosal intravenous parenteral administration syrup or injection. Such compositions may be used to treatment of multiple sclerosis and psoriasis.