The composition containing the porous silica particles of the present invention can effectively transmit a physiologically active substance to a target tissue or cell in the bloodstream by modifying the surface and suppressing aggregation and precipitation in blood. it can. In addition to the above-mentioned advantages, the composition for embolization containing the porous silica particles of the present invention has biodegradable and sustained-release physical properties and can obtain an excellent embolization effect, and also has a target tumor tissue. Alternatively, it has the advantage of excellent targeting to cells and few side effects. [Selection diagram] Fig. 1本発明の多孔性シリカ粒子を含む組成物は、表面が改質され、血液内の凝集と沈殿を抑制することにより、血流内に標的組織または細胞に生理活性物質を効果的に伝えることができる。また、本発明の多孔性シリカ粒子を含む塞栓施術用組成物は、前記利点のほか、生分解性と徐放性の物性を持って優れた塞栓施術効果を得ることができるとともに、標的腫瘍組織または細胞への標的性に優れて副作用が少ないという利点がある。【選択図】図１
