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NOVEL FAST-DISSOLVING GRANULE FORMULATION HAVING IMPROVED SOLUBILITY
专利权人:
SAM-A PHARM. CO. LTD.
发明人:
LEE, JONG HOON,SHIM, SANG BO,KIM, SANG WOOK,YI, HONG GI
申请号:
EP13870236
公开号:
EP2942052A4
申请日:
2013.01.07
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention relates to a fast-dissolving granule formulation which is dissolved quickly in the mouth. The present invention provides a fast-dissolving granule formulation which quickly dissolves within 20 seconds in the mouth when administered orally, and which causes no feelings of irritation resulting from foreign matter or residue. The granule formulation of the present invention is obtained by assembling a fast-dissolving carrier and an active ingredient, wherein the fast-dissolving carrier satisfies the conditions of having an instantaneous solubility of 30mg/ml or more, solubility of 50mg/ml or more within five minutes, and the instantaneous solubility is 90% or less than the maximum solubility. The granule formulation may achieve effects of the present invention regardless of the type of the active ingredient and therefore can be applied to various active ingredients. Further, since the present invention provides a relatively simple preparation process, a high efficiency process can be constructed at a low cost.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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