In some embodiments, the present invention provides methods of treating a tumor in a subject. In some embodiments, the methods may include a step of administering to the subject a therapeutic composition that comprises: (a) mycophenolic acid, an analogue thereof, or a derivative thereof and (b) at least one anti-neoplastic agent. In some embodiments, the anti¬ neoplastic agent may include at least one of 5-fluouracil (5-FU), paclitaxel, oxaliplatin, doxorubicin, etoposide, irinotecan, bleomycin, imiquimod, 13-cis-retinoic acid, and combinations thereof. In some embodiments, the mycophenolic acid is not derivatized. In some embodiments, the relative concentrations of the mycophenolic acid, the analogue thereof, or the derivative thereof, and the at least one anti-neoplastic agent correspond to their respective IC50 values. In some embodiments, the mycophenolic acid, the analogue thereof, or the derivative thereof, and the least one anti-neoplastic agent are present at concentrations correlating to various ratios of their IC50 values, such as 8: 1 6:1 4: 1 3: 1 2: 1 3:2 2:3 1:2 1:4 1: 6 or 1:8. In some embodiments, the methods of the present invention may be used to treat tumors associated with at least one of an oral cancer, a skin cancer, a breast cancer, a prostate cancer, precancerous lesions thereof, hyperplastic lesions thereof, and benign tumors thereof. In some embodiments, the subject to be treated is a human being, such as a human being suffering from one or more of the aforementioned cancerous or precancerous conditions.Selon certains modes de réalisation, la présente invention concerne des méthodes de traitement dune tumeur chez un sujet. Dans certains modes de réalisation, les procédés peuvent comprendre une étape dadministration au sujet dune composition thérapeutique qui comporte : (a) de lacide mycophénolique, un analogue de celui-ci ou un dérivé de celui-ci (b) au moins un agent antinéoplasique. Dans certains modes de réalisation, lagent antinéoplasi
