The present invention provides compositions comprising amorphous calcium carbonate (ACC) suitable for administration by inhalation and methods for their use in the treatment of ACC responsive diseases and conditions. Further provided are ACC compositions suitable for buccal or sublingual administration. [Selection figure] None本発明は、吸入投与に好適な非晶質炭酸カルシウム(ACC)を含む組成物、及びACC応答性疾患及び病態の治療におけるそれらの使用方法を提供する。さらに、頬側又は舌下投与に好適なACC組成物が提供される。【選択図】なし