This invention is directed to spiro-oxindole compounds of formula (I): whereink, j, Q, R1, R2a, R2b, R2c, R2d, R3a, R3b, R3c, and R3d are as defined herein,as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof； or apharmaceutically acceptable salt, solvate or prodrug thereof, which are usefulfor the treatment and/or prevention of sodium channel-mediated diseases orconditions, such as pain. Pharmaceutical compositions comprising the compoundsand methods of preparing and using the compounds are also disclosed.
