KAMOGAWA, YUMIKO,CHO, MINKWON,ARAI, NAOKO,ISHIDA, KOJI
申请号:
NZ56991006
公开号:
NZ569910A
申请日:
2006.12.20
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a monoclonal antibody which binds to an extracellular domain of human ILT7 or a fragment comprising its antigen binding region wherein the monoclonal antibody comprises the following amino acid sequences as CDR1, CDR2, and CDR3 in the heavy chain variable region and the light chain variable region: CDR1 of a heavy chain variable region: SDYAWN (SEQ ID NO: 58) CDR2 of a heavy chain variable region: YISYSGSTSYNPSLKSR (SEQ ID NO: 59) and CDR3 of a heavy chain variable region: SPPYYAMDY (SEQ ID NO:60) CDR1 of light chain variable region: KASQDVGTAVA (SEQ ID NO:61) CDR2 of a light chain variable region: WASTRHT (SEQ ID NO: 62) and CDR3 of a light chain variable region: QQYSSYPLT (SEQ ID NO:63).