Method for inducing neural precursor cells from melanocytes and a composition for treating damage of central or peripheral nervous system comprising said neural precursor cells
The present invention relates to a method for inducing neural progenitor cells by culturing melanocytes in a culture medium containing neurotrophin 3, NT3, neuregulin 1-beta1, NRG1-beta1 and forskolin, How to； A composition for treating central or peripheral nerve damage comprising neural progenitor cells induced by the above method as an active ingredient； And neuronal progenitor cells from melanocytes containing NT3, neuregulin 1-beta1 and forskolin.Skin epidermis, melanocytes, neural progenitor cells, nerve cells, Schwann cells본 발명은 멜라노세포를 신경영양인자 3(neurotrophin 3, NT3), 뉴레규린1-베타 1(neuregulin 1-beta1, NRG1-beta1) 및 폴스코린(forskolin)을 함유하는 배양액에서 배양하여 신경전구세포를 유도하는 방법； 상기 방법에 따라 유도된 신경전구세포를 유효성분으로 포함하는 중추 또는 말초 신경계 손상 치료용 조성물； 및 NT3, neuregulin 1-beta1 및 forskolin을 함유하는 멜라노세포로부터 신경전구세포 유도용 배양액에 관한 것이다.
