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DERIVATIVES OF THAILANSTATIN A, METHODS OF TREATMENT AND METHODS OF SYNTHESIS THEREOF
专利权人:
WILLIAM MARSH RICE UNIVERSITY
发明人:
Kyriacos C. NICOLAOU,Derek RHOADES,Soundarapandian M. KUMAR,Manas R. PATTANAYAK,Manjunath LAMANI
申请号:
US16308334
公开号:
US20200024283A1
申请日:
2017.06.08
申请国别(地区):
US
年份:
2020
代理人:
摘要:
In one aspect, the present disclosure provides analogs of thailanstatin of the formula wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein.
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