The invention relates to human homeobox transcription factor ventx and its regulation on the differentiation and maturation of human dendritic cells, and relates to related therapeutic and diagnostic compositions and use methods thereof.本發明涉及人同源盒轉錄因子VentX及其對人樹突狀細胞的分化和成熟的調控,並且涉及相關的治療和診斷組合物及其使用方法。