KUDUK, SCOTT D.,库杜克 史考特Ｄ,庫杜克 史考特Ｄ,SKUDLAREK, JASON W.,史库拉瑞克 杰森Ｗ,史庫拉瑞克 傑森Ｗ,库杜克 史考特D,庫杜克 史考特D,史库拉瑞克 杰森W,史庫拉瑞克 傑森W
申请号：
TW101138514
公开号：
TW201317228A
申请日:
2012.10.18
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
The present invention is directed to 2-pyridyloxy-4-nitrile compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridyl-oxy-4-nitrile compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved.本發明係關於2-吡啶氧基-4-腈化合物，其係食慾素受體之拮抗劑。本發明亦關於本文所述之該等2-吡啶氧基-4-腈化合物治療或預防涉及食慾素受體之神經及精神病症及疾病之用途。本發明亦關於包括該等化合物之醫藥組合物。本發明亦關於該等醫藥組合物預防或治療該等涉及食慾素受體之疾病之用途。
