Michael David Bell,Aneshkumar Dineshchandra Sitaram,Judata Iskandar Darma Wibawa,Paul James Tomlinson
申请号：
GB201519200
公开号：
GB2543822A
申请日:
2015.10.30
申请国别(地区):
GB
年份:
2017
代理人:
摘要：
Skin care compositions comprising O-substituted ascorbic acid derivatives, a matrix metalloproteinase inhibitor, and hibiscus and/or a peptide (I) A composition comprising: an O-substituted ascorbic acid or derivative thereof； a matrix metalloproteinase inhibitor； and hibiscus and/or a peptide, wherein the composition comprises an aqueous phase present at up to 95 wt% or up to 90 wt% of the composition is provided. Preferably the O-substituted ascorbic acid derivative is represented by formula (I) wherein R1 and R2 are independently H, C1-20alkyl, C3-20cycloalkyl, C1-20alkoxy, C2-20acyl, C6-20aryl, C1-20heterocyclic aromatic, C1-20heterocyclic non-aromatic or C3-20cycloalkenyl, in particular the O-substituted ascorbic acid derivative is 3-ethyl ascorbic acid. Preferably the matrix metalloproteinase inhibitor is selected from N-acetyl cysteine, glutathione, 2-flurildioxime, vitamin C (other than the O-substituted ascorbic acid or derivative thereof), hydrolysed rice protein, alfalfa extract, white lupin, zizyphus jujube extract, kudzu extract, vitis vinifera extract, Oenothera biennis extract or anogeissus leiocarpus extract and mixtures thereof. The composition may be in the form of an oil-in-water composition comprising 30 to 85 wt% of an aqueous phase, and 15 to 70 wt% of an oil phase. Preferably the composition is a water-in-silicone oil emulsion wherein the silicone oil is preferably a silicone elastomer. The composition is preferably used in a method of decreasing or preventing wrinkles or fine lines, skin sagging, or increasing skin firmness.
