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DRUG FOR A RESPIRATORY DISEASE
专利权人:
DAIICHI SANKYO COMPANY; LIMITED
发明人:
Sakiko Takahashi,Tsuyoshi Shinozuka,Yuki Domon,Yutaka Kitano
申请号:
BR112015022385
公开号:
BR112015022385A2
申请日:
2014.03.13
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
1/1 summary “drug for a respiratory disease” A therapeutic and / or prophylactic agent for respiratory diseases, or a therapeutic and / or prophylactic agent for mediated diseases is provided. by sodium channel. a pharmaceutical agent which contains, as an active ingredient, a compound represented by the formula (i) or a pharmaceutically acceptable salt thereof. in formula (i) each of ar and 2 1 2 ar represents a heteroaryl group or an aryl group; each of r, re 3 r represents a hydrogen atom, a halogen atom, a C-c alkyl group, a halogenated C-c alkyl group, an alkyl hydroxy group 1 6 1 6 c-c, a C1 -C6 alkoxy C1 -C6 alkyl group, a C1 -C6 cycloalkyl group or a cyano group; each rer represents a hydrogen atom, a halogen atom, a c-c alkyl group, a halogenated c-c alkyl group, a hydroxyl group, a c-c alkyl hydroxy group, a C1 -C6 alkoxy C1 -C6 alkyl, a C1 -C6 cycloalkyl group or a C1 -C6 alkoxy group; and n 1 6 3 7 1 6 represents an integer of 1-3. In this context, the heteroaryl group and the aryl group may have one or two groups which are independently selected from a halogen atom, a c-c alkyl group, a halogenated c-c alkyl group, a hydroxyl group a C1-6 alkyl hydroxy group, a C1-6 alkoxyalkyl group, a C1-6 cycloalkyl group, a carboxyl group, a cyano group, an amino group, a C1 -C6 alkylamino group and C1 -C4 dialkylamino group, and in cases where two groups are contained, groups may be the same or different from each other. () n (i)1 / 1 resumo “droga para uma doenã‡a respiratã“riaâ€� ㉠fornecido um agente terapãªutico e/ou profilã¡tico para doenã§as respiratã³rias, ou um agente terapãªutico e/ou profilã¡tico para doenã§as mediadas por canal de sã³dio. um agente farmacãªutico que contã©m, como um ingrediente ativo, um composto representado pela fã³rmula (i) ou um sal 1 farmacologicamente aceitã¡vel do mesmo. na fã³rmula (i), cada um de ar e 2 1 2 ar representa um grupo heteroarila ou um grupo arila; cada um de r , r e 3 r representa um ã¡tomo de hidrogãªnio, um ã¡t
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