Taisuke TAKAHASHI;Norio ASAI;Yasuhito NAGAI;Takafumi SHIMIZU;Keiko KAWABATA;Karl Bruce THOR;Hiroyuki KOSHIO
发明人:
Hiroyuki KOSHIO,Norio ASAI,Taisuke TAKAHASHI,Takafumi SHIMIZU,Yasuhito NAGAI,Keiko KAWABATA,Karl Bruce THOR
申请号：
US13613948
公开号：
US20130059837A1
申请日:
2012.09.13
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided is a compound which is useful as an agent for treating or preventing 5-HT2C receptor-related diseases, particularly incontinence such as stress urinary incontinence, urge urinary incontinence, mixed urinary incontinence, and the like, sexual dysfunction such as erectile dysfunction syndrome and the like, obesity, and the like. The present inventors have investigated compounds having a 5-HT2C receptor agonist activity and have found that the benzazepine compounds of the present invention have an excellent 5-HT2C receptor agonist activity, thereby completing the present invention. That is, the benzazepine compounds of the present invention have a 5-HT2C receptor agonist activity and can be used as an agent for treating or preventing 5-HT2C receptor-related diseases, particularly incontinence such as stress urinary incontinence, urge urinary incontinence, mixed urinary incontinence, and the like, sexual dysfunction such as erectile dysfunction syndrome and the like, obesity, and the like.
