Methods are provided for reducing visceral fat or reducing accumulation of visceral fat in a subject, or of reducing fat in a liver or reducing accumulation of fat in a liver of a subject, comprising administering a humanin or an active analog of humanin to the subject. Methods are also provided of increasing hepatic triglyceride secretion in a subject or of increasing hepatic microsomal triglyceride transfer protein (MTTP) expression in a subject.
