The new Lactobacillus fermentum HY7301 producing poly saccharides having immune stimulating activity and products containing thereof as effective component
구형근,안영태,허철성,KU, HYUNG KEUNKR,ANH, YOUNG TAEKR,HUH, CHUL SUNGKR
申请号：
KR1020130131932
公开号：
KR1015119760000B1
申请日:
2013.11.01
申请国别(地区):
KR
年份:
2015
代理人:
摘要：
The present invention relates to new Lactobacillus fermentum having activity of enhancing immunity and a product including the same as an active ingredient. According to the present invention, Lactobacillus fermentum induces generation of TNF-&alpha； and NO in a macrophage (Raw264.7) of a mouse and also induces generation of TNF-&alpha；, IFN-&gamma；, IL-12 in a human peripheral blood mononuclear cell (PBMC). Therefore, the Lactobacillus fermentum has activity of enhancing immunity. The Lactobacillus fermentum can be used for various products having an effect of enhancing immunity such as a pharmaceutical composition for treating and/or preventing autoimmune diseases, health functional food, a functional beverage, a fermented product and the like which include the Lactobacillus fermentum as an active ingredient.본 발명은 면역증강 활성을 가지는 신규한 락토바실러스 퍼멘텀(Lactobacillus fermentum) 및 이를 유효성분으로 함유하는 제품에 관한 것으로서, 본 발명에 따른 락토바실러스 퍼멘텀(Lactobacillus fermentum)은 마우스 대식세포(Raw264.7)에서 TNF-α 및 NO의 생성을 유도하고, 사람의 말초혈액 단핵세포(Peripheral blood mononuclear cell, PBMC)에서 TNF-α, IFN-γ, IL-12의 생성을 유도함으로써 면역 증강 활성을 가지므로 이를 유효성분으로 함유하는 면역질환 치료 및/또는 예방용 약학조성물, 건강기능식품, 기능성 음료, 발효제품 등 면역력 강화 효과를 갖는 제품에 다양하게 응용될 수 있다.
