Daniël Verhoef,Pieter H. Reitsma,Mettine H. A. Bos
申请号：
US16719875
公开号：
US20200138917A1
申请日:
2019.12.18
申请国别(地区):
US
年份:
2020
代理人:
摘要：
This disclosure relates to recombinant FXa polypeptides that can be used as antidotes to completely or partially reverse an anti-coagulant effect of a coagulation inhibitor in a subject, preferably a direct factor Xa inhibitor. Disclosed herein are recombinant factor Xa proteins and a method of completely or partially reversing an anti-coagulant effect of a coagulation inhibitor in a subject.
