INSTITUT PASTEUR;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS-
发明人:
申请号：
EP04769635.6
公开号：
EP1677815B8
申请日:
2004.09.24
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present invention relates to polypeptides that inhibit the NF-&kgr；B signaling pathway and polynucleotides encoding the same. The present invention further provides methods for the modulation of and/or treatment of inflammatory responses, oncogenesis, viral infection； the regulation of cell proliferation and apoptosis； and regulation of B or T lymphocytes in antigenic stimulation, by administering the polypeptides of the present invention to a subject in need thereof. Finally, the present invention provides a method of identifying polypeptides that modulate oligomerization of NEMO.
