Compositions for use in the treatment or prevention of influenza infection are provided and the compositions contain a 2-fucosylated oligosaccharide such as 2-fucosyllactose (2FL). The compositions can also include fructooligosaccharides (FOS). Additionally said compositions can be used for improving resistance to an influenza virus decreasing influenza in the lung decreasing influenza induced anorexia decreasing influenza induced pulmonary mucin secretion and decreasing influenza induced IgG response. They may be used in a infant or a young child.