ACADEMISCH ZIEKENHUIS LEIDEN (H.O.D.N. LUMC);LEIDEN UNIVERSITY MEDICAL CENTER
发明人:
HEEMSKERK, MIRJAM H.M.,FALKENBURG, J.H. FREDERIK
申请号:
CA2966300
公开号:
CA2966300A1
申请日:
2015.11.02
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The technology relates in part to compositions and methods for inducing an immune response against a Bob1 antigen. Provided are methods for treating hyperproliferative diseases by inducing an immune response against a Bob1 antigen; the immune response may be induced using a Bob1 polypeptide fragment, or by specifically targeting Bob1-expressing cells using T cell receptors directed against Bob1.