Wei Guobao,Kaes David R.,Drapeau Susan J.,Bhattacharyya Subhabrata
申请号：
US201514617170
公开号：
US10006705(B2)
申请日:
2015.02.09
申请国别(地区):
美国
年份:
2018
代理人:
摘要：
Methods for treating bulk bone tissue are provided. The methods comprise contacting bulk bone tissue or frozen bulk bone tissue with an effective amount of a supercritical fluid so as to dry the bulk bone tissue. In various embodiments, the supercritical fluid destroys contaminants such that the frozen bulk bone tissue is 99.9% substantially pure. In various embodiments, contaminants removed from the frozen bulk bone tissue include lipids, viruses, bacteria, pyrogens, prions, micro-organisms and/or pathogens. In some embodiments, the supercritical fluid causes a 3 log reduction of bacteria within the frozen bulk bone tissue.
