Whole expressed cell as antigen carrier, and use thereof in preparing vaccine or diagnostic agent, and screening monoclonal antibodies

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专利权人:

Formosa Biomedical Inc.

发明人:

Shun-Wen Ko

申请号：

US15288935

公开号：

US10138494B2

申请日:

2016.10.07

申请国别(地区):

US

年份:

2018

代理人:

摘要：

A mammalian cell co-transfect with an expression plasmid comprising T7 promoter and an open reading frame (ORF) of target antigen, and a vT7 recombinant vaccinia virus expressing T7 polymerase. The entire antigen expressing cell is used as a carrier of the target antigen for preparing a vaccine or diagnostic agent, and screening monoclonal antibodies.

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