THERAPY FOR DRUG-RESISTANT CANCER BY ADMINISTRATION OF ANTI-HER2 ANTIBODY/DRUG CONJUGATE

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专利权人:

LIMITED;DAIICHI SANKYO COMPANY

发明人:

Takahiro JIKOH,Yusuke OGITANI,Kazutaka YOSHIHARA,Seiko ENDO,Yoshihiko FUJISAKI

申请号：

US16334008

公开号：

US20190330368A1

申请日:

2017.10.05

申请国别(地区):

US

年份:

2019

代理人:

摘要：

As treatment effective for HER2-expressing cancer having resistance or refractoriness to an existing anti-HER2 drug, there are provided a therapeutic agent and a treatment method using an antibody-drug conjugate in which a linker and a drug represented by the formula: -(Succinimid-3-yl-N)—；CH2CH2CH2CH2CH2—；C(═；O)-GGFG-NH—；CH2—；O—；CH2—；C(═；O)—；(NH-DX) are conjugated to an anti-HER2 antibody.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/