Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors

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专利权人:

Incyte Corporation

发明人:

Rodgers, James D.,Shepard, Stacey,Maduskuie, Thomas P.,Wang, Haisheng,Falahatpisheh, Nikoo,Rafalski, Maria,Arvanitis, Argyrios G.,Storace, Louis,Jalluri, Ravi Kumar,Fridman, Jordan S.,Vaddi, Krishna

申请号：

AU2012201894

公开号：

AU2012201894A1

申请日:

2012.03.30

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

#$%^&*AU2012201894A120120419.pdf#####ABSTRACT The present invention provides heteroaryl substituted pyrrolo[2,3b]pyridines (1) and heteroaryl substituted pyrrolo[2,3-b]pyrimidines that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immunerelated diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases. (Y nZ z T=A 2 /11 \N R A R2 R3 N N H(I

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