#$%^&*AU2015101669A420151224.pdf#####ABSTRACT A composition is provided which was found to have considerable levels of cytotoxicity against tested cell lines, and also exhibited antifungal activity. This composition comprises tea tree extract and aged tea tree oil, and can be used in the treatment of cancer and agricultural plant disease. The tea tree extract is provided by a method which extracts select compounds from Melaleuca a/temifolia, and the aged tea tree oil is provided by a method of altering the chemical composition of tea tree oil.1/1 FIGURES Concentration response curve (Janbrook extracioR blend against Hs27 normal fibroblasts and A375 0 m oalnntion (elaos ) pewn reduction in cell viabiit firm three or morte exe etsErr bare indicate standard ConCentraion response Curve (Cforamnburniagainst Hs27 normal fibroblasts ami A375 malignant Maanoma) M / 6 1 A； A375 3.0 025356 0 76 400 4.2 4.50 4J 6.00 .28 050 4.75 620 LonetTbon (,g/gL) Figure 2 Concentration response cuve forjenbrook tee tree extract/oil blend against malignant neanoma cell linie (A375) and Normal dermal lbroblast (H-27) Mean values of normalised percent reduction in cell viability from three or more experiments, Eror bare indicate standard deviation,
