GILL MICHELLE A,BANCHEREAU JACQUES F,CONNOLLY JOHN E
申请号：
IN9379/DELNP/2010
公开号：
IN2010DN09379A
申请日:
2010.12.31
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
The present invention includes compositions, methods and systems for inducing immune tolerance using antigen presenting cells by infecting isolated antigen presenting cells with an effective amount of respiratory syncytial virus (RSV) or portions thereof sufficient to infect the antigen presenting celts and contacting CD4+, CD8+ or both CD4+ T cells and CDS+ T cells with the RSV-infected antigen presenting cells, wherein the CD4+, CD8+ or both CD4 and CD8+ T cells are rendered tolerogenic as measured in vitro by a mixed leukocyte reaction.
