THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人:
NICOLLS, MARK, R.,TIAN, WEN,RAJADAS, JAYAKUMAR
申请号:
EP13764988
公开号:
EP2827849A4
申请日:
2013.03.15
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Pulmonary arterial hypertension (PAH) can be prevented in persons susceptible to the diseases and PAH patients can be treated by administering an effective dose of a leukotriene inhibitor. Suitable inhibitors include leukotriene A4 hydrolase (LTA4H) inhibitors, leukotriene B4 receptor (BLT1/BLT2) antagonists, 5-lipoxygenase (5-LO) inhibitors, and 5-lipoxygenase activating protein (FLAP) inhibitors.